Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0600519
Disease: Ventricular Remodeling
Ventricular Remodeling 		0.300 Biomarker CTD_human TGFbeta(1)-Smads signal activation is correlated with ventricular remodeling following MI. 16635409

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0042109
Disease: Urticaria
Urticaria 		0.300 Biomarker CTD_human Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population. 19138248

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.400 Biomarker CTD_human Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction. 17164399

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0041948
Disease: Uremia
Uremia 		0.300 Biomarker CTD_human A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia. 19092814

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205698
Disease: Undifferentiated carcinoma
Undifferentiated carcinoma 		0.300 Therapeutic CTD_human Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. 12417722

2002
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0263628
Disease: Tumoral calcinosis
Tumoral calcinosis 		0.300 Biomarker CTD_human Genes involved in innate immunity associated with asbestos-related fibrotic changes. 24142982

2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C3489628
Disease: Thrombocytosis, Autosomal Dominant
Thrombocytosis, Autosomal Dominant 		0.300 Biomarker CTD_human PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide. 15682418

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0040028
Disease: Thrombocythemia, Essential
Thrombocythemia, Essential 		0.320 Biomarker CTD_human PDGF-A, PDGF-B, TGFbeta, and bFGF mRNA levels in patients with essential thrombocythemia treated with anagrelide. 15682418

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0271673
Disease: Symmetric Diabetic Proximal Motor Neuropathy
Symmetric Diabetic Proximal Motor Neuropathy 		0.300 Biomarker CTD_human Expression of serum and glucocorticoid-inducible kinase1 in diabetic rats and its modulation by fluvastatin. 16696316

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker CTD_human Protective effect of Gui Qi mixture on the progression of diabetic nephropathy in rats. 17177138

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 Biomarker CTD_human Use of a TGFbeta type I receptor inhibitor in mouse skin carcinogenesis reveals a dual role for TGFbeta signaling in tumor promotion and progression. 20852150

2010
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0000786
Disease: Spontaneous abortion
Spontaneous abortion 		0.300 Biomarker CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0037286
Disease: Skin Neoplasms
Skin Neoplasms 		0.310 Biomarker CTD_human Altered expression of transforming growth factor-beta 1 mRNA and protein in mouse skin carcinogenesis. 8148055

1994
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		0.310 Biomarker CTD_human Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats. 16003065

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0036690
Disease: Septicemia
Septicemia 		0.330 Biomarker CTD_human Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats. 16003065

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0243026
Disease: Sepsis
Sepsis 		0.330 Biomarker CTD_human Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats. 16003065

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0238065
Disease: Secondary Biliary Cholangitis
Secondary Biliary Cholangitis 		0.300 Biomarker CTD_human Hepatoprotective effects of diosmin and/or sildenafil against cholestatic liver cirrhosis: The role of Keap-1/Nrf-2 and P38-MAPK/NF-κB/iNOS signaling pathway. 30026087

2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.340 Biomarker PSYGENET There was a significant difference in the genotype distribution and allelic frequency of the TGFB1 +869T>C between patients with schizophrenia and healthy controls (p < 0.05). 24065520

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		0.350 Biomarker CTD_human TGF-beta 1 variants in chronic beryllium disease and sarcoidosis. 17785866

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034189
Disease: Pyemia
Pyemia 		0.300 Biomarker CTD_human Effect of chemically modified tetracycline on transforming growth factor-beta1 and caspase-3 activation in liver of septic rats. 16003065

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Biomarker CTD_human CTGF can be upregulated by TGF-beta1 and appears to play an important role in the development of pulmonary fibrosis. 19817698

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Biomarker CTD_human Abnormal expression of TGF-beta1 is believed to play an important role in the pathogenesis of a number of chronic inflammatory and immune lung diseases, including asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. 16365456

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Biomarker CTD_human Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard. 15286001

2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.700 Biomarker CTD_human Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice. 16324872

2006